| Registro completo |
| Provedor de dados: |
Acta Amazonica
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| País: |
Brazil
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| Título: |
In vitro studies of the anthelmintic activity of Picrolemma sprucei Hook. f. (Simaroubaceae)
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| Autores: |
Nunomura,Rita de Cássia Saraiva
Silva,Ellen Cristina Costa da
Oliveira,Denilson Ferreira
Garcia,Adriana Mello
Boeloni,Jankerle Neves
Nunomura,Sergio Massayoshi
Pohlit,Adrian Martin
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| Data: |
2006-01-01
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| Ano: |
2006
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| Palavras-chave: |
Picrolemma pseudocoffea Ducke
Haemonchus contortus
Neosergeolide
Isobrucein B
Caferana
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| Resumo: |
1300 ppm (1.3 g / L), water and ethanol extracts prepared from stems or roots of Picrolemma sprucei Hook. f. were lethal (85-90 % mortality) in vitro to Haemonchus contortus (Barber Pole Worm) larvae, a gastrointestinal nematode parasite found in domestic and wild ruminants. Neosergeolide and isobrucein B were isolated in 0.0083 and 0.0070 % yield from dry, ground P. sprucei stems (0.89 kg). Neosergeolide, isobrucein B and the anthelmintic drug standard levamisole all caused comparable mortality rates (68-77 %) in vitro to H. contortus at similar concentrations (81-86 ppm). The anthelmintic activity of P. sprucei infusions (teas), alcohol extracts, and neosergeolide and isobrucein B, has therefore been demonstrated for the first time.
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| Tipo: |
Info:eu-repo/semantics/article
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| Idioma: |
Inglês
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| Identificador: |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672006000300006
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| Editor: |
Instituto Nacional de Pesquisas da Amazônia
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| Relação: |
10.1590/S0044-59672006000300006
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| Formato: |
text/html
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| Fonte: |
Acta Amazonica v.36 n.3 2006
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| Direitos: |
info:eu-repo/semantics/openAccess
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